WHAT 'YOUR OLD CANCER?
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Scientific American (How Old is your cancer?)
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A patient receives a diagnosis of pancreatic cancer has only a 5% chance of surviving for five years, a heartbreaking prognosis that scientists have long struggled to understand.
Scientists at Johns Hopkins University have sequenced the genome of seven people who had died from pancreatic cancer in late stage. Cancer cells are cells that have accumulated multiple mutations, particularly at the expense of specific genes that code for proteins critical in controlling proper cell cycle. Through the analysis of tumor cells to such patients the scientists were able to literally trace back over time, through mathematical models and to rebuild some sort of family tree of the mutations that these cells had undergone. course, these technologies are not yet commercially available, but early detection through optical tests along with blood or saliva should allow in the future to detect the disease early.
Sources: Scientific American
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